Mutagenicity—New Horizons in Genetic Toxicology
نویسندگان
چکیده
منابع مشابه
Genetic toxicology: web resources.
Genetic toxicology is the scientific discipline dealing with the effects of chemical, physical and biological agents on the heredity of living organisms. The Internet offers a wide range of online digital resources for the field of Genetic Toxicology. The history of genetic toxicology and electronic data collections are reviewed. Web-based resources at US National Library of Medicine (NLM), inc...
متن کاملStudies Genetic Toxicology and Human
the Journal of Craniofacial Genetics and Developmental Biology, 1985, vol 5, is dedicated to the memory of Dr Samuel Pruzansky, an internationally renowned worker in the field of craniofacial malformations until his death in 1984. Among his many achievements, Dr Pruzansky organised the first international symposium on craniofacial malformations in 1959 and founded the first Center for Craniofac...
متن کاملEvaluating the genetic toxicology of DNA-based products using existing genetic toxicology assays.
Unlike the development of drugs based on small chemical entities there are no conventional regulatory toxicity studies established for DNA-based products. As the potential for insertional mutagenesis is of particular concern for gene therapy, we have investigated the mutagenicity of model non-viral DNA-based products at the HPRT locus in Chinese hamster V79 cells. Cultures were transfected with...
متن کاملToxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.
The unprecedented advances in molecular biology during the last two decades have resulted in a dramatic increase in knowledge about gene structure and function, an immense database of genetic sequence information, and an impressive set of efficient new technologies for monitoring genetic sequences, genetic variation, and global functional gene expression. These advances have led to a new sub-di...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1983
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1983.117